Chicken Actin, Cytoplasmic 2 (ACTG1) ELISA Kit
689€ (96 tests)
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name
Chicken Actin, Cytoplasmic 2 (ACTG1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx356563
tested applications
ELISA
Description
Chicken Actin, Cytoplasmic 2 (ACTG1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Chicken Actin, Cytoplasmic 2 (ACTG1) concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Actin, Cytoplasmic 2 (ACTG1) |
| Reactivity | Chicken |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 pg/ml - 100 pg/ml |
| Sensitivity | 0.94 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ACT,ACTG,DFNA20,DFNA26 |
| Background | Elisa kits for ACTG1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACTG1 encodes gamma-actin, a key cytoskeletal protein found primarily in non-muscle cells where it contributes to the maintenance of the cytoskeleton's integrity and dynamics. As a highly conserved isoform of actin, ACTG1 is crucial for cellular processes such as migration, adhesion, intracellular trafficking, and division. It is predominantly expressed in epithelial cells and is involved in the organization of cell junctions and maintenance of tissue structure. Mutations in the ACTG1 gene have been linked to autosomal dominant progressive hearing loss (DFNA20/26) due to its role in maintaining the structural integrity of stereocilia in the cochlea. Beyond its structural role, ACTG1 interacts with a range of actin-binding proteins, regulating the assembly and disassembly of actin filaments in response to cellular signaling. Dysregulation or mutations in ACTG1 are also associated with cancer progression and metastasis, highlighting its role in cell motility and invasion. Its ubiquitous presence and functional versatility underscore its critical role in both cellular architecture and dynamic cellular processes.
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Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, is a cytoplasmic actin found in nonmuscle cells.
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