Centromere Protein A (CENPA) Antibody

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52€ (10 µg)

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935106861
info@markelab.com
name
Centromere Protein A (CENPA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013943
tested applications
ELISA, IHC

Description

Rabbit polyclonal antibody against CENPA protein. Immunogen region is N-terminal.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Centromere Protein A (CENPA)
Immunogen: The antiserum was produced against synthesized peptide derived from N-terminal of human CENPA.
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
IHC: 1/50 - 1/100, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P49450
Background
Antibody anti-CENPA
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4) 2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].

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