CDK-Activating Kinase Assembly Factor MAT1 (MNAT1) Cell ELISA Kit

513.5€ (96 tests)
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935106861
info@markelab.com
name
CDK-Activating Kinase Assembly Factor MAT1 (MNAT1) Cell ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx595769
tested applications
ELISA
Description
MAT1 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | CDK-Activating Kinase Assembly Factor MAT1 (MNAT1) |
Reactivity | Human, Mouse, Rat |
Detection Method | Colorimetric |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Tested Applications | ELISA |
Availability | Shipped within 1-2 weeks. The validity for this kit is at least 6 months |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P51948 |
Gene ID | 4331 |
OMIM | 602659 |
Background | Elisa kits for MNAT1 |
Status | RUO |
Note | Validity: 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
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MNAT1 antibody
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase(CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain(CTD) of its large subunit(POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
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