MNAT1 antibody
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935106861
info@markelab.com
name
MNAT1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05252
tested applications
ELISA, WB, IF, IP
Description
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase(CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain(CTD) of its large subunit(POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | menage a trois homolog 1, cyclin H assembly factor(Xenopus laevis) (MNAT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 36 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P51948 |
| Gene ID | 4331 |
| Alias | CDK-activating kinase assembly factor MAT1,CDK7/cyclin-H assembly factor,Cyclin-G1-interacting protein,Menage a trois,RING finger protein 66,RING finger protein MAT1,p35,p36,MNAT1,CAP35,MAT1,RNF66 |
| Background | Antibody anti-MNAT1 |
| Status | RUO |
| Note | Mol. Weight 36 kDa |
Descripción
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MNAT1 antibody
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase(CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain(CTD) of its large subunit(POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Ver Producto