CD9 Antigen (CD9) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
CD9 Antigen (CD9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173618
tested applications
WB, IHC, IF/ICC
Description
CD9 Antigen (CD9) Antibody is a Mouse Monoclonal antibody against CD9 Antigen (CD9).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD9 Antigen (CD9) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC: 5-30 µg/ml, IF/ICC: 5-30 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Clone ID | N630 |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21926 |
| Alias | MIC3,MRP-1,BTCC-1,DRAP-27,TSPAN29,TSPAN-29,Tetraspanin-29,Motility-related protein,Leukocyte antigen MIC3,Cell growth-inhibiting gene 2 protein,5H9 antigen |
| Background | Antibody anti-CD9 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
CD9 is a member of the tetraspanin superfamily, a group of transmembrane proteins involved in various biological processes, particularly in cell adhesion, migration, proliferation, and signaling. CD9 is ubiquitously expressed on the surface of various cell types, including platelets, leukocytes, epithelial cells, endothelial cells, and germ cells. It plays a critical role in cell-cell interactions, especially in the context of immune responses, reproduction, cancer metastasis, and viral infection. One of the unique features of tetraspanins, including CD9, is their ability to organize membrane microdomains known as tetraspanin-enriched microdomains (TEMs). These microdomains function as platforms that regulate the spatial organization of other membrane proteins such as integrins, growth factor receptors, and co-receptors, thus modulating their signaling activity. CD9, in particular, interacts with several key molecules, including integrins (α6β1, α3β1), epidermal growth factor receptor (EGFR), and immunoglobulin superfamily proteins.
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