Human CD9 Antigen (CD9) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein CD9
proveedor
Abbexareference
abx168683Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human CD9 Antigen Protein, also known as Motility Related Protein (MRP1), is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
CD9 is a member of the tetraspanin superfamily, a group of transmembrane proteins involved in various biological processes, particularly in cell adhesion, migration, proliferation, and signaling. CD9 is ubiquitously expressed on the surface of various cell types, including platelets, leukocytes, epithelial cells, endothelial cells, and germ cells. It plays a critical role in cell-cell interactions, especially in the context of immune responses, reproduction, cancer metastasis, and viral infection. One of the unique features of tetraspanins, including CD9, is their ability to organize membrane microdomains known as tetraspanin-enriched microdomains (TEMs). These microdomains function as platforms that regulate the spatial organization of other membrane proteins such as integrins, growth factor receptors, and co-receptors, thus modulating their signaling activity. CD9, in particular, interacts with several key molecules, including integrins (α6β1, α3β1), epidermal growth factor receptor (EGFR), and immunoglobulin superfamily proteins.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
CD9 Antigen (CD9)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 39.7 kDa Observed MW (SDS-PAGE): 40 kDa Concentration: Prior to lyophilization: 300 µg/ml Sequence Fragment: Ser112-Ile195 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD9
dry ice
No
availability
Shipped within 5-7 working days.
alias
MIC3,MRP-1,BTCC-1,DRAP-27,TSPAN29,TSPAN-29,Tetraspanin-29,Motility-related protein,Leukocyte antigen MIC3,Cell growth-inhibiting gene 2 protein,5H9 antigen
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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