CD81 antigen (CD81) Antibody (FITC)
260€ (50 µl)
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935106861
info@markelab.com
name
CD81 antigen (CD81) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx341468
Description
CD81 antigen (CD81) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human CD81.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD81 antigen (CD81) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60033 |
| NCBI Accession | NP_004347.1 |
| Alias | CVID6,S5.7,CD81 antigen,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28, |
| Background | Antibody anti-CD81 |
| Status | RUO |
Descripción
CD81, also known as TAPA-1 (Target of the Anti-Proliferative Antibody 1), is a member of the tetraspanin family, a group of proteins that are widely expressed across various tissues and cell types. Tetraspanins are integral membrane proteins involved in a variety of biological processes, including cell adhesion, migration, proliferation, and signal transduction. CD81 has a well-established role in immune cell function, particularly in the regulation of B and T cell activity, as well as in viral infections. Most notably, CD81 is a critical component in the entry process of hepatitis C virus (HCV) into host cells. The CD81 gene is located on chromosome 11p15.5 and encodes a protein that is involved in the formation of tetraspanin-enriched microdomains. These microdomains facilitate the assembly of various signaling complexes at the cell membrane, influencing the function of associated proteins. CD81 is widely expressed on multiple cell types, including lymphocytes, hepatocytes, epithelial cells, and fibroblasts
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