CD59 Glycoprotein (CD59) Antibody
286€ (50 µg)
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name
CD59 Glycoprotein (CD59) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421403
tested applications
FCM
Description
CD59 Glycoprotein (CD59) Antibody is a Mouse Monoclonal antibody for the detection of CD59 Glycoprotein (CD59) in Human samples.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD59 Glycoprotein (CD59) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | K047 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13987 |
| Gene ID | 966 |
| NCBI Accession | NP_000602.1 |
| Alias | CD59 blood group,1F5,EJ16,EJ30,EL32,G344,MIN1,MIN2,MIN3,MIRL,HRF20,MEM43,MIC11,MSK21,16.3A5,HRF-20,MAC-IP,CD59 glycoprotein,MAC-inhibitory protein,MAC-IP,Membrane attack complex inhibition factor,MACIF |
| Background | Antibody anti-CD59 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
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