CD50 Antibody (PE)
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935106861
info@markelab.com
Precio
400€ (100 tests)
Antibody anti-ICAM3
proveedor
Abbexareference
abx139542Tested Applications
FCMreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
CD50 Antibody is a Mouse Monoclonal against CD50.
Background
Intercellular Adhesion Molecule 3 (ICAM3), also known as CD50, is a member of the immunoglobulin superfamily (IgSF) that plays a crucial role in cell-cell adhesion and immune system regulation. It is expressed predominantly on leukocytes, especially resting lymphocytes, and interacts with integrins to mediate various immune responses, including leukocyte trafficking, T-cell activation, and antigen recognition. ICAM3 is particularly involved in the early stages of immune responses, functioning as a ligand for leukocyte function-associated antigen-1 (LFA-1), an integrin found on T cells and other leukocytes. ICAM-3 acts as a facilitator of immunological synapse formation, helping leukocytes adhere to antigen-presenting cells and promoting signaling pathways critical for immune activation. Its interaction with integrins also promotes adhesion between leukocytes and endothelial cells, an important step in the migration of immune cells to sites of inflammation or infection. ICAM-3 is essential in regulating leukocyte dynamics and activation during immune surveillance and host defense.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
CD50
host
Mouse
conjugation
PE
tested applications
FCM
buffer
Stabilizing PBS solution containing 15 mM sodium azide.
size 1
100 tests
storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
or code
ICAM3
dry ice
No
availability
Shipped within 5-12 working days.
alias
CD50,CDW50,ICAM-R,Intercellular adhesion molecule 3
uniprot id
note
This product is for research use only.
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