CD45RA Antigen (CD45RA/PTPRC) Antibody
299€ (0.1 mg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
CD45RA Antigen (CD45RA/PTPRC) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139821
Tested Applications
WB, IHC, FCM, IP
Description
CD45RA Antibody is a Mouse Monoclonal against CD45RA.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD45RA Antigen (CD45RA/PTPRC) Immunogen: Human thymocytes and T lymphocytes. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | FCM: 0.3-4 μg/ml. Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b |
| Clone ID | G127 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | WB, IHC, FCM, IP |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P08575 |
| Gene ID | 5788 |
| Alias | LCA,LY5,B220,CD45,L-CA,T200,CD45R,GP180,IMD105,CD45,Leukocyte common antigen,Receptor-type tyrosine-protein phosphatase C |
| Background | Antibody anti-PTPRC |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PTPRC, also known as CD45, is a receptor-type tyrosine phosphatase primarily expressed in hematopoietic cells. It regulates antigen receptor signaling in lymphocytes by dephosphorylating inhibitory residues on Src family kinases such as Lck and Fyn. Structurally, PTPRC has an extracellular domain, a single transmembrane region, and two cytoplasmic phosphatase domains, with the first being catalytically active. It is critical for T-cell and B-cell activation, development, and immune response regulation. Mutations in PTPRC are linked to severe immunodeficiency disorders, including SCID, and its overexpression is associated with autoimmune diseases and leukemia.
Productos relacionados
Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody
PTPRC Antibody is a Rabbit Polyclonal antibody against PTPRC. The protein encoded by this gene is a member of the protei…
Ver producto
Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody
CD45, also known as TPRC (protein tyrosine phosphatase, receptor type, C). The protein encoded by this gene is a member …
Ver producto Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody
PTPRC Antibody is a Mouse Monoclonal against PTPRC.…
Ver producto