CD44 Antigen (CD44) Antibody

Este producto es parte de CD44 - CD44 molecule
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260€ (50 µl)

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935106861
info@markelab.com
name
CD44 Antigen (CD44) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211318
tested applications
ELISA, WB

Description

CD44 Antibody is a Rabbit Polyclonal against CD44.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCD44 Antigen (CD44)
HostRabbit
ReactivityHuman
Recommended DilutionELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationAntigen Affinity Chromatography.
Size 150 µl
Size 2100 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP16070
Gene ID960
AliasIN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor
BackgroundAntibody anti-CD44
StatusRUO

Descripción

CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.

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