CD4 (FITC) / CD8 (PE) Combination Antibody
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Description
CD4 (FITC) / CD8 (PE) Combination Antibody is an antibody cocktail consisting of two monoclonal antibodies:
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD4/CD8 |
| Host | Rat |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal, Monoclonal |
| Conjugation | FITC, PE |
| Isotype | IgG2a, IgG2a |
| Size 1 | 100 tests |
| Form | Lyophilized |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C or -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04235, P11942, P22646, P24161, P25918 |
| Alias | T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4 |
| Background | Antibody anti-CD4 |
| Status | RUO |
Descripción
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
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anti- CD4 antibody
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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