ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) Antibody (FITC)
65€ (50 tests)
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Name
ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx229422
Tested Applications
FCM
Description
ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) antibody (FITC) is a Rat monoclonal antibody against ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) |
| Host | Rat |
| Reactivity | Mouse |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 5 µl per test (106 cells per 100 µl sample). Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG2a Kappa |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.2, containing 0.09% stabilizer. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at the original concentration at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P56528 |
| Gene ID | 12494 |
| Alias | ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1 |
| Background | Antibody anti-CD38 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.
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