CD32 Protein

Este producto es parte de FCGR2B - Fc gamma receptor Iib
Product Graph
234€ (2 µg)

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935106861
info@markelab.com
name
CD32 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263324
tested applications
SDS-PAGE

Description

FCGR2B is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
FCGR2B
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
100 µg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P31994
Alias
CD32,FCG2,CD32B,FCGR2,IGFR2,FCGR2C,FcGRIIB,FcRII-c,FcgammaRIIb,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b
Background
Protein FCGR2B
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

FCGR2B (Fc gamma receptor IIB), also known as CD32B, is a low-affinity receptor for the Fc portion of IgG antibodies, primarily responsible for regulating immune responses by mediating inhibitory signaling. It plays a crucial role in the balance between activation and inhibition of immune cells, preventing excessive inflammation and autoimmunity. Unlike its closely related receptor, FCGR2A, which triggers activating signals, FCGR2B is the only inhibitory receptor within the Fc gamma receptor family. This receptor is predominantly expressed on B cells, dendritic cells, macrophages, and other immune cells. FCGR2B is part of the larger family of Fc gamma receptors (FcγRs), which bind the Fc region of immunoglobulin G (IgG) to mediate immune responses such as phagocytosis, cytokine release, and the clearance of immune complexes. Its inhibitory role is vital in the prevention of autoimmune reactions and the modulation of inflammatory responses.

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