CD30 Ligand (TNFSF8) Antibody (FITC)
494€ (100 tests)
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935106861
info@markelab.com
name
CD30 Ligand (TNFSF8) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx270390
tested applications
FCM
Description
Cluster Of Differentiation 30 Ligand (CD30L) Antibody (FITC) is a Rabbit Polyclonal Antibody (
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD30 Ligand (TNFSF8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32971 |
| Gene ID | 944 |
| OMIM | 603875 |
| Alias | Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand |
| Background | Antibody anti-TNFSF8 |
| Status | RUO |
Descripción
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
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