CD30 Ligand (TNFSF8) Antibody
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935106861
info@markelab.com
Precio
221€ (50 µg)
Antibody anti-TNFSF8
proveedor
Abbexareference
abx323356Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
TNFSF8 Antibody is a Rabbit Polyclonal against TNFSF8.
Background
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
CD30 Ligand (TNFSF8)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
size 1
50 µg
size 2
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
TNFSF8
dry ice
No
availability
Shipped within 5-10 working days.
alias
Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand
uniprot id
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