CD30 Ligand (TNFSF8) Antibody
260€ (100 µl)
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935106861
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name
CD30 Ligand (TNFSF8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx103901
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Cluster Of Differentiation 30 Ligand (CD30L).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: CD30 Ligand (TNFSF8) Immunogen: abx065920 - CD30L/TNFSF8 (Leu60-Ile227) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32971 |
| Gene ID | 944 |
| OMIM | 603875 |
| Alias | Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand |
| Background | Antibody anti-TNFSF8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
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Human CD30 Ligand (TNFSF8) Protein
Human Cluster Of Differentiation 30 Ligand (CD30L) is a recombinant Human protein expressed in E. coli.
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