CD28 Antibody
403€ (100 µg)
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935106861
info@markelab.com
name
CD28 Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx831586
tested applications
ELISA, WB
Description
CD28 Antibody is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD28, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD28 |
| Host | Human |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG4 |
| Expression | Recombinant |
| Purity | > 95% |
| Purification | Purified from cell culture supernatants by Protein A/G chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS. pH 7.4. |
| Availability | Shipped within 7-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Tp44,T-cell-specific surface glycoprotein CD28 |
| Background | Antibody anti-CD28 |
| Status | RUO |
| Note | Concentration: Batch-dependent, typically between 0.5-2.0 mg/ml. - |
Descripción
CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.
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