CD231 Antibody (FITC)
364€ (100 tests)
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Name
CD231 Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx140516
Tested Applications
FCM
Description
CD231 Antibody (FITC) is a Mouse Monoclonal against CD231.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD231 Immunogen: Human T-ALL cell line THP-6. |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 4 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 |
| Clone ID | R193 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P41732 |
| Gene ID | 7102 |
| Alias | Membrane component chromosome X surface marker 1,A15,MXS1,CD231, MRX58,CCG-B7,TM4SF2,XLID58,T-cell acute lymphoblastic leukemia-associated antigen 1,TALLA-1 |
| Background | Antibody anti-TSPAN7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Tetraspanin 7 (TSPAN7) is a member of the tetraspanin superfamily, a group of membrane proteins involved in various cellular functions such as signaling, adhesion, and intracellular trafficking. Tetraspanins are characterized by their distinctive structure, containing four transmembrane domains. TSPAN7 is primarily expressed in the central nervous system, particularly in neurons, and is also found in certain immune cells. TSPAN7 is of interest due to its involvement in neurological processes and its role in neurodevelopmental disorders, most notably X-linked intellectual disability (XLID). Mutations or dysregulation of TSPAN7 have been implicated in cognitive deficits, autism spectrum disorders, and other neurological conditions, highlighting its importance in normal brain function. The primary role of TSPAN7 appears to be in facilitating cell-cell interactions and maintaining synaptic function. Through its association with other proteins in the tetraspanin web—an organized network of tetraspanins and their partner proteins—TSPAN7 modulates cellular signaling pathways crucial for neuronal growth, differentiation, and communication. These functions make TSPAN7 essential for neural development and synaptic plasticity, processes that underlie learning and memory.
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