CD1c Antibody

Product specifications

Primary Antibodies

CD1c

Mouse

Human

FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.

Monoclonal

APC

IgG1 Kappa

I754

100 tests

FCM

Stabilizing PBS solution containing 15 mM sodium azide.

Shipped within 5-12 working days.

Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.

No

P29017

911

R7,CD1,CD1A,BDCA1,T-cell surface glycoprotein CD1c

Antibody anti-CD1c

RUO

Descripción

The CD1C molecule is a member of the CD1 family of glycoproteins, which play a critical role in the immune system by presenting lipid and glycolipid antigens to T cells. Unlike major histocompatibility complex (MHC) class I and II molecules, which primarily present peptide antigens, CD1 molecules specialize in the presentation of lipids, making them essential players in immune responses against lipid-containing pathogens like mycobacteria. CD1C, in particular, is one of the most studied isoforms in the CD1 family due to its role in presenting antigens to T cells, especially CD1c-restricted T cells, which are important in the defense against bacterial infections, especially those involving mycobacteria. CD1C is expressed predominantly on antigen-presenting cells (APCs), such as dendritic cells, B cells, and macrophages, which are crucial for initiating adaptive immune responses. The molecule plays a significant role in shaping the immune response to lipid antigens, facilitating the recognition and elimination of microbial invaders, especially those with complex lipid envelopes, such as Mycobacterium tuberculosis

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