CD158f Antibody (PE)

Este producto es parte de KIR2DL5A - Killer cell immunoglobulin-like receptor 2DL5A
CD158f Antibody (PE)

Pida mas información

935106861

info@markelab.com

Precio

400€ (100 tests)

Antibody anti-KIR2DL5A

proveedor

Abbexa

reference

abx140146

Tested Applications

FCM

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

CD158f Antibody is a Mouse Monoclonal against CD158f.


Background

Killer cell immunoglobulin-like receptor 2DL5A (KIR2DL5A) is a member of the KIR family, which plays a crucial role in immune regulation, especially in natural killer (NK) cell and some T-cell activities. These receptors allow immune cells to differentiate between normal cells and those that may be infected, stressed, or malignant. KIR2DL5A, like other inhibitory KIR receptors, is known for its role in maintaining immune tolerance by providing inhibitory signals to prevent NK cells from attacking healthy tissues. This regulation is achieved through interactions with specific ligands, mainly human leukocyte antigen (HLA) class I molecules on target cells. However, the specific HLA ligands for KIR2DL5A remain under research, with some studies suggesting unique ligand interactions within this receptor subtype. KIR2DL5A is located on chromosome 19 within the KIR gene cluster, which exhibits considerable genetic diversity across individuals. This diversity allows NK cells to adapt to various pathogenic and environmental pressures. The polymorphic nature of KIR genes like KIR2DL5A contributes to variations in immune responses between individuals, which can influence susceptibility to infections, autoimmune diseases, and cancer.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

CD158f


host

Mouse


conjugation

PE


tested applications

FCM


buffer

Stabilizing PBS solution containing 15 mM sodium azide.


size 1

100 tests


storage

Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.


or code

KIR2DL5A


dry ice

No


availability

Shipped within 5-12 working days.


alias

CD158F,KIR2DL5,KIR2DL5.1,KIR2DL5.3


note

This product is for research use only.


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