CD120b Antibody (Biotin)

117€ (25 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
CD120b Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx228343
tested applications
FCM
Description
CD120b Antibody (Biotin) is a Mouse Monoclonal Antibody against CD120b.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD120b |
Host | Hamster |
Reactivity | Mouse |
Clonality | Monoclonal |
Conjugation | Biotin |
Isotype | IgG |
Size 1 | 25 µg |
Size 2 | 100 µg |
Tested Applications | FCM |
Buffer | PBS with 0.05% Proclin300, 1% BSA. |
Availability | Shipped within 5-15 working days. |
Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
Dry Ice | No |
UniProt ID | P25119 |
Gene ID | 21938 |
Alias | Tumor necrosis factor receptor superfamily member 1B,p75,TBPII,TNFBR,TNFR2,CD120b,TNFR1B,TNFR80,TNF-R75,p75TNFR,TNF-R-II,Tumor necrosis factor receptor 2,p80 TNF-alpha receptor |
Background | Antibody anti-TNFRSF1B |
Status | RUO |
Descripción
TNFRSF1B, also known as Tumor Necrosis Factor Receptor Superfamily Member 1B or TNFR2, is a cell surface receptor predominantly expressed on immune cells, including regulatory T cells (Tregs), endothelial cells, and neurons. TNFR2 is one of the two primary receptors for tumor necrosis factor-alpha (TNF-α), along with TNFR1 (TNFRSF1A). Although TNFR1 and TNFR2 both bind TNF-α, they have unique and overlapping roles within immune responses. TNFR2 primarily activates pathways that promote cell survival, tissue regeneration, and anti-inflammatory responses, differentiating it from TNFR1, which is more commonly associated with apoptosis and pro-inflammatory signaling. The TNFRSF1B gene is located on chromosome 1p36.22 and encodes a receptor of 461 amino acids. TNFR2 is a key component in regulating inflammation, modulating T cell activity, and contributing to vascular health. Its interaction with TNF-α can activate both canonical (NF-κB) and non-canonical pathways, resulting in varying cellular responses depending on the cellular environment and receptor activation context.
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