CD11c Antibody (AF488)

Este producto es parte de ITGAX - integrin subunit alpha X
Product Graph
104€ (50 tests)

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935106861
info@markelab.com
name
CD11c Antibody (AF488)
category
Primary Antibodies
provider
Abbexa
reference
abx228050
tested applications
FCM

Description

CD11c Antibody (AF488) is a Mouse Monoclonal Antibody against CD11c.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
CD11c
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
AF488
Isotype
IgG
Size 1
50 tests
Size 2
100 tests
Size 3
200 tests
Tested Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
Q9QXH4
Gene ID
16411
Alias
CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95
Background
Antibody anti-ITGAX
Status
RUO

Descripción

Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.

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