CD11c Antibody (AF488)
104€ (50 tests)
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Name
CD11c Antibody (AF488)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx228050
Tested Applications
FCM
Description
CD11c Antibody (AF488) is a Mouse Monoclonal Antibody against CD11c.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD11c |
| Host | Hamster |
| Reactivity | Mouse |
| Detection Method | Laser Line: 488 Excitation/Emission: 495/520 |
| Clonality | Monoclonal |
| Conjugation | AF488 |
| Isotype | IgG |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q9QXH4 |
| Gene ID | 16411 |
| Alias | CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95 |
| Background | Antibody anti-ITGAX |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.
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