CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
CNOT1 Antibody is a Rabbit Polyclonal against CNOT1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Immunogen: CCR4-NOT transcription complex, subunit 1 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 240-250 kDa, 174 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | A5YKK6 |
| Gene ID | 23019 |
| OMIM | 604917 |
| Background | Antibody anti-CNOT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
CNOT1 antibody
Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element(ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem(ES) cell identity.
Ver Producto
CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
CNOT1 Antibody is a Rabbit Polyclonal antibody against CNOT1.
Ver Producto
CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
Ccr4-Not Transcription Complex, Subunit 1 Antibody is a Rabbit Polyclonal antibody against Ccr4-Not Transcription Complex, Subunit 1.
Ver Producto