CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
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Description
Ccr4-Not Transcription Complex, Subunit 1 Antibody is a Rabbit Polyclonal antibody against Ccr4-Not Transcription Complex, Subunit 1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CCR4-NOT Transcription Complex Subunit 1 (CNOT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | A5YKK6 |
| Gene ID | 23019 |
| NCBI Accession | NP_001252541.1, NM_001265612.1, NP_057368.3, NM_016284.4 |
| OMIM | 604917 |
| Background | Antibody anti-CNOT1 |
| Status | RUO |
Descripción
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CNOT1 antibody
Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element(ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem(ES) cell identity.
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CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
CNOT1 Antibody is a Rabbit Polyclonal antibody against CNOT1.
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CCR4-NOT Transcription Complex Subunit 1 (CNOT1) Antibody
Ccr4-Not Transcription Complex, Subunit 1 Antibody is a Rabbit Polyclonal antibody against Ccr4-Not Transcription Complex, Subunit 1.
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