Caspase Recruitment Domain Family Member 6 (CARD6) Antibody
52€ (10 µg)
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935106861
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name
Caspase Recruitment Domain Family Member 6 (CARD6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013028
tested applications
ELISA, WB, IHC, IF/ICC
Description
Rabbit polyclonal antibody against CARD6 protein. Immunogen region is N-terminal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Caspase Recruitment Domain Family Member 6 (CARD6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, IHC: 1/50 - 1/100, IF/ICC: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BX69 |
| Alias | CINCIN1 |
| Background | Antibody anti-CARD6 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
CARD6 is part of the caspase recruitment domain family of proteins and is involved in the regulation of immune cell signaling, particularly in response to stress and inflammation. CARD6 is expressed in various tissues, including immune cells, and is believed to play a role in controlling NF-κB signaling pathways. While it shares the CARD domain with other family members like CARD9 and CARD8, CARD6 has distinct functions, including its involvement in apoptosis and inflammatory responses. It can modulate both pro-inflammatory and anti-inflammatory signaling, making it an important protein in the balance of immune activation. In certain conditions, such as chronic inflammatory diseases, the activity of CARD6 can become dysregulated, contributing to excessive inflammation. Further understanding of CARD6’s role in immune signaling may provide insights into therapeutic strategies for diseases involving chronic inflammation and autoimmune disorders.
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