Caspase Recruitment Domain Family Member 17 (CARD17) Antibody

260€ (50 µl)
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935106861
info@markelab.com
name
Caspase Recruitment Domain Family Member 17 (CARD17) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx339889
tested applications
ELISA, IHC
Description
CARD17 Antibody is a Rabbit Polyclonal against CARD17.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Caspase Recruitment Domain Family Member 17 (CARD17) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/1000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q5XLA6 |
Gene ID | 440068 |
Alias | CARD17,Caspase-1 inhibitor INCA,Inhibitory caspase recruitment domain protein |
Background | Antibody anti-CARD17P |
Status | RUO |
Descripción
CARD17P refers to a pseudogene within the caspase recruitment domain (CARD) family. The CARD family is characterized by a conserved domain involved in mediating protein-protein interactions in apoptotic and inflammatory signaling pathways. As a pseudogene, CARD17P is considered a non-functional relic of gene duplication or evolutionary processes, lacking the ability to produce a functional protein. However, pseudogenes like CARD17P can still exert regulatory roles, such as through transcriptional interference, RNA-mediated mechanisms, or modulation of their functional gene counterparts. CARD family genes are integral to immune responses and apoptotic processes, and while CARD17P itself may not encode an active protein, its presence could reflect genomic evolutionary adaptations or provide insight into the regulation and evolution of CARD-related pathways. Further investigation into pseudogenes like CARD17P continues to reveal their potential contributions to genetic and epigenetic regulatory landscapes.
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