Caspase Recruitment Domain Family Member 17 (CARD17) Antibody
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Pida mas información
935106861
info@markelab.com
Precio
260€ (50 µl)
Antibody anti-CARD17P
proveedor
Abbexareference
abx339889Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
CARD17 Antibody is a Rabbit Polyclonal against CARD17.
Background
CARD17P refers to a pseudogene within the caspase recruitment domain (CARD) family. The CARD family is characterized by a conserved domain involved in mediating protein-protein interactions in apoptotic and inflammatory signaling pathways. As a pseudogene, CARD17P is considered a non-functional relic of gene duplication or evolutionary processes, lacking the ability to produce a functional protein. However, pseudogenes like CARD17P can still exert regulatory roles, such as through transcriptional interference, RNA-mediated mechanisms, or modulation of their functional gene counterparts. CARD family genes are integral to immune responses and apoptotic processes, and while CARD17P itself may not encode an active protein, its presence could reflect genomic evolutionary adaptations or provide insight into the regulation and evolution of CARD-related pathways. Further investigation into pseudogenes like CARD17P continues to reveal their potential contributions to genetic and epigenetic regulatory landscapes.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Caspase Recruitment Domain Family Member 17 (CARD17)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purification
Antigen Affinity Chromatography.
recommended dilution
ELISA: 1/1000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CARD17P
dry ice
No
availability
Shipped within 5-10 working days.
alias
CARD17,Caspase-1 inhibitor INCA,Inhibitory caspase recruitment domain protein
uniprot id
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