Caspase recruitment domain-containing protein 6 (CARD6) Antibody
169€ (20 µl)
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935106861
info@markelab.com
name
Caspase recruitment domain-containing protein 6 (CARD6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx348831
tested applications
ELISA, IHC, IF/ICC
Description
Caspase recruitment domain-containing protein 6 (CARD6) Antibody is a Rabbit Polyclonal antibody for the detection of Human CARD6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Caspase recruitment domain-containing protein 6 (CARD6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BX69 |
| Gene ID | 84674 |
| Alias | CINCIN1 |
| Background | Antibody anti-CARD6 |
| Status | RUO |
Descripción
CARD6 is part of the caspase recruitment domain family of proteins and is involved in the regulation of immune cell signaling, particularly in response to stress and inflammation. CARD6 is expressed in various tissues, including immune cells, and is believed to play a role in controlling NF-κB signaling pathways. While it shares the CARD domain with other family members like CARD9 and CARD8, CARD6 has distinct functions, including its involvement in apoptosis and inflammatory responses. It can modulate both pro-inflammatory and anti-inflammatory signaling, making it an important protein in the balance of immune activation. In certain conditions, such as chronic inflammatory diseases, the activity of CARD6 can become dysregulated, contributing to excessive inflammation. Further understanding of CARD6’s role in immune signaling may provide insights into therapeutic strategies for diseases involving chronic inflammation and autoimmune disorders.
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