Cartilage Oligomeric Matrix Protein, HEK Protein
234€ (2 µg)
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name
Cartilage Oligomeric Matrix Protein, HEK Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262574
Description
COMP HEK is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | COMP HEK |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P49747 |
| Alias | MED,CTS2,EDM1,EPD1,TSP5,PSACH,THBS5,TSP-5,Thrombospondin-5 |
| Background | Protein COMP |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
COMP is a non-collagenous extracellular matrix protein primarily expressed in cartilage, tendons, and ligaments where it plays a key role in maintaining tissue structure and mechanical integrity COMP interacts with collagen fibrils and other matrix components to facilitate fibril assembly and stabilize the extracellular matrix COMP also functions as a chaperone during collagen secretion, promoting proper folding and export from chondrocytes Mutations in COMP are associated with skeletal dysplasias such as pseudoachondroplasia and multiple epiphyseal dysplasia, which result in abnormal cartilage development, joint pain, and short stature COMP overexpression has been observed in osteoarthritis and rheumatoid arthritis, where its elevated levels contribute to cartilage degradation and inflammation COMP is also implicated in cardiovascular diseases where it regulates vascular smooth muscle cell function and extracellular matrix remodeling
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