Carnitine O-Palmitoyltransferase 1, Brain Isoform (CPT1C) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
CPT1C Antibody is a Rabbit Polyclonal against CPT1C.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carnitine O-Palmitoyltransferase 1, Brain Isoform (CPT1C) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TCG5 |
| Gene ID | 126129 |
| NCBI Accession | NP_001129524.1, NM_001136052.2, NP_001186681.1, NM_001199752.2 |
| OMIM | 608846 |
| Background | Antibody anti-CPT1C |
| Status | RUO |
Descripción
Related Products
Carnitine O-Palmitoyltransferase 1, Brain Isoform (CPT1C) Antibody
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
Ver Producto