Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171577
tested applications
WB, IHC, IF/ICC
Description
Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Antibody is a Mouse Monoclonal antibody against Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | CD67,CGM6,CD66b,NCA-95,Non-specific cross-reacting antigen NCA-95,Carcinoembryonic antigen-related cell adhesion molecule 8 |
| Background | Antibody anti-CEACAM8 |
| Status | RUO |
Descripción
CEACAM8, also known as CD66b or carcinoembryonic antigen-related cell adhesion molecule 8, is a glycoprotein that belongs to the CEA (carcinoembryonic antigen) family, a subgroup of the immunoglobulin superfamily (IgSF). CEACAM8 is mainly expressed on granulocytes, a type of white blood cell, particularly neutrophils, eosinophils, and basophils. It is involved in regulating the function of these immune cells, including adhesion to endothelial cells, activation, and degranulation, which are critical in inflammation and immune defense. CEACAM8 plays a key role in facilitating the migration of granulocytes during inflammatory responses and contributes to the regulation of cell-cell adhesion in tissues. As an immune cell marker, CEACAM8 is often used in clinical settings to identify neutrophils and their activation states in various conditions, including infections and inflammatory diseases.
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