Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein
1872€ (1 mg)
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935106861
info@markelab.com
name
Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652779
tested applications
WB, SDS-PAGE
Description
Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.2 kDa Observed MW (SDS-PAGE): 37 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln35-Asp320 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | CD67,CGM6,CD66b,NCA-95,Non-specific cross-reacting antigen NCA-95,Carcinoembryonic antigen-related cell adhesion molecule 8 |
| Background | Protein CEACAM8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CEACAM8, also known as CD66b or carcinoembryonic antigen-related cell adhesion molecule 8, is a glycoprotein that belongs to the CEA (carcinoembryonic antigen) family, a subgroup of the immunoglobulin superfamily (IgSF). CEACAM8 is mainly expressed on granulocytes, a type of white blood cell, particularly neutrophils, eosinophils, and basophils. It is involved in regulating the function of these immune cells, including adhesion to endothelial cells, activation, and degranulation, which are critical in inflammation and immune defense. CEACAM8 plays a key role in facilitating the migration of granulocytes during inflammatory responses and contributes to the regulation of cell-cell adhesion in tissues. As an immune cell marker, CEACAM8 is often used in clinical settings to identify neutrophils and their activation states in various conditions, including infections and inflammatory diseases.
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