Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652779
tested applications
WB, SDS-PAGE
Description
Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Gln35-Asp320 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 35.2 kDa Observed MW (SDS-PAGE): 37 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | CD67,CGM6,CD66b,NCA-95,Non-specific cross-reacting antigen NCA-95,Carcinoembryonic antigen-related cell adhesion molecule 8 |
| Background | Protein CEACAM8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
CEACAM8, also known as CD66b or carcinoembryonic antigen-related cell adhesion molecule 8, is a glycoprotein that belongs to the CEA (carcinoembryonic antigen) family, a subgroup of the immunoglobulin superfamily (IgSF). CEACAM8 is mainly expressed on granulocytes, a type of white blood cell, particularly neutrophils, eosinophils, and basophils. It is involved in regulating the function of these immune cells, including adhesion to endothelial cells, activation, and degranulation, which are critical in inflammation and immune defense. CEACAM8 plays a key role in facilitating the migration of granulocytes during inflammatory responses and contributes to the regulation of cell-cell adhesion in tissues. As an immune cell marker, CEACAM8 is often used in clinical settings to identify neutrophils and their activation states in various conditions, including infections and inflammatory diseases.
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