Carbohydrate Sulfotransferase 14 (CHST14) Antibody
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Description
CarbohydRate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Antibody is a Rabbit Polyclonal antibody against CarbohydRate (N-Acetylgalactosamine 4-0) Sulfotransferase 14.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carbohydrate Sulfotransferase 14 (CHST14) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NCH0 |
| Gene ID | 113189 |
| OMIM | 601776 |
| Background | Antibody anti-CHST14 |
| Status | RUO |
Descripción
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CHST14 antibody
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
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Carbohydrate Sulfotransferase 14 (CHST14) Antibody
This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.
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Carbohydrate Sulfotransferase 14 (CHST14) Antibody
CarbohydRate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Antibody is a Rabbit Polyclonal antibody against CarbohydRate (N-Acetylgalactosamine 4-0) Sulfotransferase 14.
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