Cadherin, Neuronal (CDH2) Antibody

Descripción

This gene is a classical cadherin from the cadherin superfamily.The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.The protein functions during gastrulation and is required for establishment of left-right asymmetry.At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.