Cadherin 5 Phospho-Tyr731 (CDH5 pY731) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Cadherin 5 Phospho-Tyr731 (CDH5 pY731) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325827
tested applications
ELISA, WB, IHC
Description
CDH5 (pY731) Antibody is a Rabbit Polyclonal against CDH5 (pY731).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cadherin 5 Phospho-Tyr731 (CDH5 pY731) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Data | Modification: Phosphorylation // Target Modification: Tyr731 |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P33151 |
| Gene ID | 1003 |
| Alias | Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin |
| Background | Antibody anti-CDH5 |
| Status | RUO |
Descripción
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
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