Cadherin 5 (CDH5) Antibody (Biotin)
169€ (20 µg)
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name
Cadherin 5 (CDH5) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx315377
tested applications
ELISA
Description
CDH5 Antibody (Biotin) is a Rabbit Polyclonal against CDH5 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cadherin 5 (CDH5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P33151 |
| Gene ID | 1003 |
| NCBI Accession | NP_001786.2, NM_001795.4 |
| OMIM | 601120 |
| Alias | Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin |
| Background | Antibody anti-CDH5 |
| Status | RUO |
Descripción
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
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