Cadherin-5 (CDH5) Antibody (APC / Cyanine 7)
468€ (100 tests)
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Name
Cadherin-5 (CDH5) Antibody (APC / Cyanine 7)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx347019
Tested Applications
FCM
Description
Cadherin-5 (CDH5) Antibody (APC / Cyanine 7) is a Mouse Monoclonal against Cadherin-5 (CDH5).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cadherin-5 (CDH5) Immunogen: Human endothelial cells. |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | APC / Cyanine 7 |
| Isotype | IgG1 Kappa |
| Clone ID | W671 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P33151 |
| Gene ID | 1003 |
| Alias | Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin |
| Background | Antibody anti-CDH5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
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