Cadherin 5 (CDH5) Antibody
221€ (50 µg)
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Name
Cadherin 5 (CDH5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx159421
Tested Applications
ELISA, IHC
Description
CDH5 Antibody is a Mouse Monoclonal against CDH5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cadherin 5 (CDH5) Immunogen: Synthetic Peptide of VE-Cadherin at AA range of 670-750. |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P33151 |
| Alias | Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin |
| Background | Antibody anti-CDH5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
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