Cadherin-1 / E-Cadherin (CDH1) Antibody

Descripción

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Características del producto

clonality

Monoclonal

reactivity

Human, Mouse

immunogen target

Cadherin-1 / E-Cadherin (CDH1)

host

Mouse

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purification

Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

CDH1

dry ice

availability

Shipped within 5-10 working days.

alias

Uvomorulin,UVO,CDHE,ECAD,LCAM,Arc-1,BCDS1,CD324,CAM 120/80,Epithelial cadherin

uniprot id

https://www.uniprot.org/uniprotkb/P12830

NCBI accession

NP_004351.1

note

This product is for research use only.

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