C5a Anaphylatoxin Chemotactic Receptor 1 (C5AR1) Antibody

Este producto es parte de C3a-C5a - Complement component Receptor
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312€ (50 µg)

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935106861
info@markelab.com
name
C5a Anaphylatoxin Chemotactic Receptor 1 (C5AR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421445
tested applications
FCM

Description

C5a Anaphylatoxin Chemotactic Receptor 1 (C5AR1) Antibody is a Human Monoclonal antibody for the detection of C5a Anaphylatoxin Chemotactic Receptor 1 (C5AR1) in Human samples.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
C5a Anaphylatoxin Chemotactic Receptor 1 (C5AR1)
Host
Human
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Clone ID
W826
Purity
> 95%
Purification
Purified by Protein A/G affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4.
Availability
Shipped within 5-12 working days.
Storage
Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
P21730
Gene ID
728
NCBI Accession
NP_001727.1
Alias
C5AR1,CD88,C5A,C5AR,C5R1,C5a anaphylatoxin chemotactic receptor,C5a-R,complement C5a receptor,complement component 5a receptor 1
Background
Antibody anti-C5AR1
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

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Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).

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