Butyrophilin Subfamily 3 Member A1 (BTN3A1) Antibody

Name: Butyrophilin Subfamily 3 Member A1 (BTN3A1) Antibody
Brand: Abbexa
SKU: abx027428
Price: 281.25 EUR
Availability: OnlineOnly

Este producto es parte de BTN3A - butyrophilin subfamily 3 member A

Pida mas información

935106861

info@markelab.com

Precio

281.25€ (80 µl)

Antibody anti-BTN3A1

proveedor

Abbexa

reference

abx027428

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM].

Background

BTN3A, a member of the butyrophilin (BTN) family, is a type I transmembrane protein primarily involved in the modulation of immune responses. BTN3A is encoded by the BTN3A1, BTN3A2, and BTN3A3 genes, which are part of the larger BTN gene family located on chromosome 6 in humans. The BTN family is a subset of the immunoglobulin (Ig) superfamily and shares structural similarities with the B7 family of co-stimulatory molecules. BTN3A proteins are expressed in a variety of tissues, including immune cells like T cells and dendritic cells, indicating their significant role in immune system regulation. BTN3A1 isoform is the most extensively studied and is known for its role in the activation of γδ T cells. BTN3A1 interacts with phosphoantigens and facilitates their recognition by γδ T cells, leading to immune activation.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Butyrophilin Subfamily 3 Member A1 (BTN3A1)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

BTN3A1

dry ice

availability

Shipped within 5-10 working days.

alias

BTF5,BT3.1,CD277,BTN3.1

uniprot id

https://www.uniprot.org/uniprotkb/O00481

note

This product is for research use only.

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anti- BTN3A1 antibody

proveedor

FineTest

reference

FNab00983

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

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