Butyrophilin-Like Protein 3 (BTNL3) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Butyrophilin-Like Protein 3 (BTNL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025978
tested applications
ELISA, WB, FCM
Description
BTNL3 is expressed in small intestine, colon, testis, spleen, and leukocyte and plays a role in lipid metabolism. Two isoforms have been described.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Butyrophilin-Like Protein 3 (BTNL3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UXE8 |
| Alias | BTNLR,BTN9.1,COLF4100,Butyrophilin-like receptor,Butyrophilin-like protein 3 |
| Background | Antibody anti-BTNL3 |
| Status | RUO |
Descripción
Butyrophilin like 3 (BTNL3) is a member of the butyrophilin family involved in immune system modulation, particularly in the context of antigen-presenting cells and T cell activation. BTNL3 is structurally similar to butyrophilin-like proteins known for regulating γδ T cells, which play a critical role in innate immunity and tumor surveillance. It is expressed in epithelial tissues and is thought to influence immune responses at barrier sites. Although its specific interactions and signaling mechanisms are less well characterized than other butyrophilin-like proteins, BTNL3 is of interest for its potential role in immune checkpoint regulation and its implications for cancer immunotherapy. Further studies aim to explore its role in immune evasion and its therapeutic utility as a target for enhancing anti-tumor immunity.
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