Brevican Core Protein (Bcan) Antibody

Background

Brevican (BCAN) is a member of the lectican family of proteoglycans, which are essential components of the extracellular matrix in the central nervous system (CNS). The lecticans, including aggrecan, versican, neurocan, and brevican, play crucial roles in the formation and maintenance of the neural extracellular matrix. Brevican is particularly abundant in the brain and spinal cord, where it contributes to the structural integrity and functionality of neural tissues. It was first identified in the early 1990s and has since been recognized for its involvement in various neural processes, including synaptic plasticity, axonal guidance, and neural repair.