Natriuretic Peptides B (NPPB) Antibody
383.5€ (100 µl)
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Name
Natriuretic Peptides B (NPPB) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx016076
Tested Applications
ELISA, IHC
Description
Natriuretic Peptides B (NPPB) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin.ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain.BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties.It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload.These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues.This ring structure shows high homology between different natriuretic.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Natriuretic Peptides B (NPPB) Immunogen: Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP, conjugated to KLH. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P16860 |
| Gene ID | 4879 |
| OMIM | 600295 |
| Background | Antibody anti-NPPB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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