Name: BH3-Interacting Domain-Containing Protein 3 (Hrk) Antibody
Brand: Abbexa
SKU: abx027221
Price: 281.25 EUR
Availability: OnlineOnly

Descripción

Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X (L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

BH3-Interacting Domain-Containing Protein 3 (Hrk)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purification

Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

HRK

dry ice

availability

Shipped within 5-10 working days.

alias

DP5,HARAKIRI,BID3,BH3-interacting domain-containing protein 3,Neuronal death protein DP5

uniprot id

https://www.uniprot.org/uniprotkb/O00198

note

This product is for research use only.

Quizá le pueda interesar