Beta-Site APP Cleaving Enzyme 2 (bACE2) Antibody

Descripción

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by bACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Beta-Site APP Cleaving Enzyme 2 (bACE2)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, FCM

purification

Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

bACE2

dry ice

availability

Shipped within 5-10 working days.

uniprot id

https://www.uniprot.org/uniprotkb/Q9Y5Z0

note

This product is for research use only.

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