Beta-Secretase 1 (BACE1) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Beta-Secretase 1 (BACE1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224061
tested applications
ELISA, WB, IF/ICC, FCM
Description
BACE1 Antibody is a Mouse Monoclonal against BACE1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-Secretase 1 (BACE1) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P56817, P56818 |
| Gene ID | 23621 |
| OMIM | 604252 |
| Background | Antibody anti-BACE1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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BACE1 antibody
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
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