BACE1 antibody
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935106861
info@markelab.com
name
BACE1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00781
tested applications
ELISA, WB, IP, IHC
Description
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | beta-site APP-cleaving enzyme 1 (BACE1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70-75 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P56817 |
| Gene ID | 23621 |
| Alias | Beta-secretase 1,Aspartyl protease 2 (ASP2, Asp 2),Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1),Memapsin-2,Membrane-associated aspartic protease 2,BACE1,BACE,KIAA1149 |
| Background | Antibody anti-BACE1 |
| Status | RUO |
| Note | Mol. Weight 70-75 kDa |
Descripción
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BACE1 antibody
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Ver Producto