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Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Primary Antibodies
polyclonal
human,mouse,rat
beta-site APP-cleaving enzyme 1
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IP, IHC
70-75 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACE1
BACE, KIAA1149
This product is for research use only.
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-bet...
Precio a consultar
Ver másResponsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-bet...
Precio a consultar
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