Beta-Galactoside Alpha-2,6-Sialyltransferase 1 / CD75 (ST6GAL1) Antibody (PE)
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Description
Beta-Galactoside Alpha-2,6-Sialyltransferase 1 / CD75 (ST6GAL1) Antibody (PE) is a PE-conjugated Mouse monoclonal antibody for the detection of Beta-Galactoside Alpha-2,6-Sialyltransferase 1 / CD75 (ST6GAL1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-Galactoside Alpha-2,6-Sialyltransferase 1 / CD75 (ST6GAL1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 μl/100 μl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgM Kappa |
| Clone ID | P682 |
| Purification | Purified by size exclusion chromatography. |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | TBS pH 8.0, containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| Background | Antibody anti-ST6GAL1 |
| Status | RUO |
Descripción
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This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
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ST6GAL1 (β-galactoside α-2-6 sialyl transferase1; also known as ST6N or CD75) is a sialyltransferase mediating the glycosylation of proteins and lipids to form functionally important glycoproteins and glycolipids in the Golgi compartment. It is principally expressed in liver, placenta and skeletal muscle. ST6GAL1 undergoes proteolytic process to generate soluble form from membrane form. Western blot analysis of human liver using this antibody detects both isoforms between 43-50 kDa. Higher molecular weight of bands around 50-70 kDa can also be observed with unknown reason.
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